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We have extention which can allow you integrate dhtmlxGrid with form (availible in PRO version only). You can see example here http://dhtmlx.com/docs/products/dhtmlxGrid/samples/interaction_other_components/pro_form.html. 

If your grid has checkboxes responce to the server side will looks like that:

array(2) {
  ["gridbox_4_2"]=>
  string(1) "0"
  ["gridbox_5_2"]=>
  string(1) "1"
}