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Destroying layuots

I have a nested layout scheme and want to destroy the child layout in a parent cell to replace it with something else - what is the proper/clean way to destroy a layout?

There is no any kind of method for correct layout's desctuction.
You can do the following:
(for example cell "a" containt layout you want to destroy)
dhxLayout.cells("a").layout = null;
dhxLayout.cells("a").attachObject(...); // just attach another object/component